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Invitrogen™ PAX6 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA1801

Catalog No. PA1801

  • $456.65 / Each of 1

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    Reg : $619.50

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Description

Description

PA1-801 detects PAX6 from human, mouse, rat, non-human primate and ovine samples. This antibody does not detect bovine PAX6 by Western blot. PA1-801 has been successfully used in Western blot, immunofluorescence, and immunoprecipitation procedures. By Western blot, this antibody detects a ~47 kDa protein representing PAX6. The PA1-801 immunogen is a synthetic peptide corresponding to residues C R(267) E E K L R N Q R R Q A S N T P S H I(285) of mouse PAX6. This sequence is completely conserved in humans, mice, frogs, and chickens. This peptide (Product # PEP-207) is available for use in neutralization and control experiments.

This gene encodes paired box gene 6, one of many human homologs of the Drosophila melanogaster gene prd. In addition to the hallmark feature of this gene family, a conserved paired box domain, the encoded protein also contains a homeo box domain. Both domains are known to bind DNA, and function as regulators of gene transcription. This gene is expressed in the developing nervous system, and in developing eyes. Mutations in this gene are known to cause ocular disorders such as aniridia and Peter's anomaly. Alternatively spliced transcript variants encoding either the same or different isoform have been found for this gene.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

PAX6
Polyclonal
Unconjugated
PAX6
1500038E17Rik; AEY11; AN; AN2; Aniridia; aniridia type II protein; D11S812E; Dey; Dickie's small eye; FVH1; Gsfaey11; Keratitis; MGC17209; MGDA; oculorhombin; paired box 6; paired box gene 6; Paired Box Gene-6; paired box homeotic gene 6; paired box homeotic gene-6; paired box protein Pax-6; Pax6; Pax-6; PAX6 protein; Sey; small eye; transcription factor; WAGR
Rabbit
Antigen affinity chromatography
RUO
18508, 25509, 5080, 554264
-20°C, Avoid Freeze/Thaw Cycles
Liquid
Immunoprecipitation, Western Blot, Immunocytochemistry
1 mg/mL
PBS with 1mg/mL BSA and 0.05% sodium azide
P26367, P63015, P63016
PAX6
Synthetic peptide corresponding to residues C R(267) E E K L R N Q R R Q A S N T P S H I(285) of mouse PAX6.
100 μg
Primary
Human, Mouse, Rat, Monkey, Sheep
Antibody
IgG
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