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Invitrogen™ Paxillin Polyclonal Antibody
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Catalog No. PIPA534910
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100 μL
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PIPA534910 100 μL
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Catalog No. PIPA534910 Supplier Invitrogen™ Supplier No. PA534910
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: 293T, A431, HeLa, HepG2, rat brain, GFP-human Paxillin-transfected 293T, MDA-MB-231. Predicted reactivity: Mouse (94%), Chicken (82%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Paxillin is a focal adhesion protein and a substrate for several tyrosine kinases such as src, FAK, and p210BRC/ABL. The tyrosine phosphorylation of paxillin is affected by conditions that change cell-cell adhesion. Paxillin associates tightly with FAK and Crk through its SH2 domain. This interaction is independent of the extracellular matrix. Although paxillin was initially discovered in fibroblasts, its phosphorylation may also be important during neurite extension during differentiation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Paxillin
Applications Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.48 mg/mL
Conjugate Unconjugated
Formulation PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene PXN
Gene Accession No. P49023, Q66H76, Q8VI36
Gene Alias adaptor protein; AW108311; AW123232; FLJ16691; hCG_1778014; I79_001229; myocardial ischemic preconditioning associated protein 7; Pax; PAX-1; PAXI; Paxillin; paxillin a; paxillin alpha; pxn; pxna; testicular tissue protein Li 134; TGFB1I1; transforming growth factor beta 1 induced transcript 1; wu:fw71f12
Gene Symbols PXN
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human Paxillin. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 19303, 360820, 5829
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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