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Tocris Bioscience™ Paxilline
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Catalog No. 200610
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10 mg
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Catalog No. Quantity
20-061-0 10 mg
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Catalog No. 20-061-0 Supplier Tocris Bioscience™ Supplier No. 2006/10
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Description

SERCA ATPase blocker. Also potent BKCa channel blocker

Potent blocker of high-conductance Ca2+-activated K+ (BKCa, KCa1.1) channels. Binds to the α-subunit of BKCa (Ki = 1.9 nM for block of currents in α-subunit-expressing oocytes) and enhances binding of charybdotoxin to BKCa channels in vascular smooth muscle. Also inhibits sarco/endoplasmic reticulum Ca2+-ATPase (IC50 = 5 - 50 μM).

Chemical Identifiers

CAS 57186-25-1
Molecular Formula C27H33NO4

Specifications

Quantity 10 mg
Formula Weight 435.56
Purity >98%
Molecular Weight (g/mol) 435.564
Chemical Name or Material Paxilline

Safety and Handling

Recommended Storage Desiccate at -20°C
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