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  5. Tocris Bioscience™ PB 28 dihydrochloride

Tocris Bioscience™ PB 28 dihydrochloride
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Catalog No. 256250
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Quantity:
10 mg
50 mg
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This item is not returnable. View return policy

Description

High affinity σ2 agonist

PB 28 dihydrochloride is a high affinity σ2 receptor agonist (Ki values are 0.8 and 15.2 nM for σ2 and σ1 receptors respectively) that displays minimal affinity at other receptors. Inhibits electrically evoked twitch in guinea pig bladder and ileum (EC50 values are 2.62 and 3.96 μM respectively). Displays antiproliferative and cytotoxic effects in SK-N-SH neuroblastoma and C6 glioma cells.

Specifications

Chemical Name or Material 1-Cyclohexyl-4-[3-(1,2,3,4-tetrahydro-5-methoxy-1-naphthalenyl)propyl]piperazine dihydrochloride
CAS 172907-03-8
Assay Percent Range >99%
Quantity 50 mg
Solubility Soluble to 20mM with gentle warming in water
Molecular Formula C24H38N2O.2HCl
Formula Weight Observed MW: 443.5

For Research Use Only

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