PCDHGC5 Mouse anti-Human, Clone: OTI2E1, liquid, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene TA807819

Catalog No. 50-168-1782

Description

This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.

Specifications

• Antigen: PCDHGC5
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: Q9Y5F6
• Gene Symbols: PCDHGC5
• Immunogen: Human recombit protein fragment corresponding to amino acids 35-258 of human PCDHGC5 produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI2E1
• Conjugate: Unconjugated
• Gene: PCDHGC5
• Gene Alias: PCDH-GAMMA-C5
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 56097
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid