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Invitrogen™ PCSK1 Polyclonal Antibody
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Catalog No. PIPA529832
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100 μL
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PIPA529832 100 μL
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Catalog No. PIPA529832 Supplier Invitrogen™ Supplier No. PA529832
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: HepG2, HCT116. Predicted reactivity: Mouse (99%), Rat (100%), Zebrafish (93%), Pig (100%), Bovine (98%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein is a type I proinsulin-processing enzyme that plays a key role in regulating insulin biosynthesis. It is also known to cleave proopiomelanocortin, prorenin, proenkephalin, prodynorphin, prosomatostatin and progastrin. Mutations in this gene are thought to cause obesity. This encoded protein is associated with carcinoid tumors. The use of alternate polyadenylation sites has been found for this gene. Multiple alternatively spliced transcript variants have been described for this gene but their full length nature is not known.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PCSK1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.52 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene PCSK1
Gene Accession No. P29120, P63239
Gene Alias Att-1; Bdp; BMIQ12; EC 3.4.21.93; Furin homolog; LOW QUALITY PROTEIN: neuroendocrine convertase 1; NEC 1; NEC1; Nec-1; Neuroendocrine convertase 1; PC1; PC3; PCSK1; Phpp-1; Prohormone convertase 1; prohormone convertase 1/3; prohormone convertase 3; propeptide-processing protease; Proprotein convertase 1; proprotein convertase subtilisin/kexin type 1; Protein convertase subtilisin / kexin type I; Protein convertase subtilisin / kexin, type I; SPC3
Gene Symbols PCSK1
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human PC1/3. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18548, 5122
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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