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Invitrogen™ PCYT2 Polyclonal Antibody
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Catalog No. PA1545
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100 μg
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PA1545 100 μg
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Catalog No. PA1545 Supplier Invitrogen™ Supplier No. PA1545
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Rabbit Polyclonal Antibody

PA1-545 detects ethanolaminephosphate cytidyltransferase (ECT) protein in human, rat, mouse and non-human primate samples. PA1-545 has successfully been used in Western blot procedures. By Western blot, this antibody detects an ~50 kDa protein representing ECT from C3H/10T1/2 cell lysates. PA1-545 immunizing peptide corresponds to amino acid residues 157-172 from human ECT protein. This immunizing peptide (PEP-241) can be used for neutralization and control experiments.

ECT (ethanolaminephosphate cytidyltransferase) is an important regulatory enzyme in the pathway for phosphatidylethanolamine (PE) biosynthesis. PE functions in cell signalling, membrane fusion, platelet activation, and cell cycle progression. Specialized forms of PE exist as plasmologens, natural cannabinoid anadimade, and glycosylated PE. The ECT enzyme acts in the second of three catalysis steps to produce CDP-ethanolamine from phosphoethanolamine (P-Etn). Study of ECT could help determine the role of plasmologens in disease, specifically lipid disorders such as peroxisomal diseases as well as neuronal degeneration associated with Alzheimer's disease.
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Specifications

Antigen PCYT2
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.4 mg/mL
Conjugate Unconjugated
Formulation tris with 1mg/mL BSA, glycine and 0.02% thimerosal
Gene PCYT2
Gene Accession No. O88637, Q922E4, Q99447
Gene Alias 1110033E03Rik; CTP:phopshoethanolamine cytidylyltransferase; CTP:phosphoethanolamine cytidylyltransferase; ET; ethanolamine-phosphate cytidylyltransferase; PCYT2; phosphate cytidylyltransferase 2, ethanolamine; phosphorylethanolamine transferase
Gene Symbols PCYT2
Host Species Rabbit
Immunogen Synthetic Peptide: C(157) T K A H H S S Q E M S S E Y R E(172).
Purification Method Affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5833, 68671, 89841
Target Species Human, Mouse, Rat, Monkey
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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