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Invitrogen™ PCYT2 Polyclonal Antibody
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Catalog No. PIPA590366
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100 μL
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PIPA590366 100 μL
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Catalog No. PIPA590366 Supplier Invitrogen™ Supplier No. PA590366
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: MIRNGRGAAG GAEQPGPGGR RAVRVWCDGC YDMVHYGHSN QLRQARAMGD YLIVGVHTDE EIAKHKGPPV FTQEERYKMV QAIKWVDEVV PAAPYVTTLE TLDKYNCDFC VHGNDITLTV DGRDTYEEVK QAGRYRECKR TQGVSTTDLV GRMLLVTKAH HSSQEMSSEY REYADSFGKC PGGRNPWTGV SQFLQTSQKI IQFASGKEPQ PGETVIYVAG AFDLFHIGHV DFLEKVHRLA ERPYIIAGLH FDQEVNHYKG KNYPIMNLHE RTLSVLACRY VSEVVIGAPY AVTAELLSHF KVDLVCHGKT EIIPDRDGSD PYQEPKRRGI FRQIDSGSNL TTDLIVQRII TNRLEYEARN QKKEAKELAF LEAARQQAAQ PLGERDGDF; Positive Samples: MCF7, HepG2, 293T, Mouse brain, Mouse liver, Rat liver.

ECT (ethanolaminephosphate cytidyltransferase) is an important regulatory enzyme in the pathway for phosphatidylethanolamine (PE) biosynthesis. PE functions in cell signalling, membrane fusion, platelet activation, and cell cycle progression. Specialized forms of PE exist as plasmologens, natural cannabinoid anadimade, and glycosylated PE. The ECT enzyme acts in the second of three catalysis steps to produce CDP-ethanolamine from phosphoethanolamine (P-Etn). Study of ECT could help determine the role of plasmologens in disease, specifically lipid disorders such as peroxisomal diseases as well as neuronal degeneration associated with Alzheimer's disease.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PCYT2
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 1.12 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene PCYT2
Gene Accession No. O88637, Q922E4, Q99447
Gene Alias 1110033E03Rik; CTP:phopshoethanolamine cytidylyltransferase; CTP:phosphoethanolamine cytidylyltransferase; ET; ethanolamine-phosphate cytidylyltransferase; PCYT2; phosphate cytidylyltransferase 2, ethanolamine; phosphorylethanolamine transferase
Gene Symbols PCYT2
Host Species Rabbit
Immunogen Recombinant protein (or fragment).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5833, 68671, 89841
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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