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  5. Tocris Bioscience™ PD 98059

Tocris Bioscience™ PD 98059
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Catalog No. 121350R
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Quantity:
1 mg
10 mg
50 mg
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This item is not returnable. View return policy

Description

MEK inhibitor

PD 98059 is an inhibitor of mitogen-activated protein kinase kinase (MKK/ MEK). Acts by binding to the inactivated form of MEK, thereby preventing its phosphorylation by cRAF or MEK kinase (IC50 = 2-7 μM). Inhibits cell growth and proliferation in acute myelogenous leukemia (AML) cell lines; causes G1 arrest by blocking p53-dependent p21 induction. Enhances embryonic stem cell self-renewal.

Specifications

CAS 167869-21-8
Quantity 50 mg
Molecular Formula 2-(2-Amino-3-methoxyphenyl)-4 H-1-benzopyran-4-one
Product Type PD 98059
Purity 98%
Molecular Weight (g/mol) M.W. (Observed): 267.28
Inhibitors PD 98059

For Research Use Only

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