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CPC Scientific cyclo(AcTyr-MeAla-Asn-Pro-His-Leu-Hyp-Trp-Ser-Trp(Me)-MeNle-MeNle-Orn-Cys)-Gly-NH2 (trifluoroacetate salt) 0.5MG

Supplier: CPC Scientific CANC022A
WL12 peptide selectively binds to programmed death ligand 1 (PD-L1), an immune checkpoint protein that is overexpressed in many cancer cell lines. Tumor PD-L1 expression contributes to immune system depression and is indicative of a tumor?s response to PD-L1 and PD-1.SEQUENCE: cyclo(AcTyr-MeAla-Asn-Pro-His-Leu-Hyp-Trp-Ser-Trp(Me)-MeNle-MeNle-Orn-Cys)-Gly-NH2 (trifluoroacetate salt)(Thioether bridge: Cys14-Ac-Tyr)ONE-LETTER SEQUENCE: cyclo(AcY-MeANPHL-Hyp-WSW(Me)-MeNle-MeNle-OC)-G-NH2 (trifluoroacetate salt)(Thioether bridge: C14-Ac-Y)MOLECULAR FORMULA: C91H128N22O20SMOLECULAR WEIGHT: 1882.19STORAGE CONDITIONS: -20 5 CCAS REGISTRY NUMBER: SYNONYMS: RESEARCH AREA: CancerCITATIONS:Lesniak, Wojciech G. et al. Molecular Imaging 18 (2019)?Chatterjee
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