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PD-L1 Recombinant Rabbit Monoclonal Antibody (BLR020E), Bethyl Laboratories

Rabbit Recombit Monoclonal Antibody

$157.08 - $595.98

Specifications

Antigen PD-L1
Clone BLR020E
Applications Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
Classification Recombinant Monoclonal
Conjugate Unconjugated
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
50-157-1294
Encompass_Preferred
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Bethyl Laboratories, Inc
A700020T
10 μL
Each for $157.08
Only null left
Add to Cart
 
50-157-1293
Encompass_Preferred
View Documents
Bethyl Laboratories, Inc
A700020
100 μL
Each for $595.98
Only null left
Add to Cart
 
Description

Description

The recommended shelf life for this product is 1 year from date of receipt. Application Note: For ICC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections. For IHC, epitope retrieval with citrate buffer pH 6.0 is recommende

Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by cognate peptides bound to MHC molecules on antigen-presenting cells (APC). T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC. PD-1 can bind two different but related ligands, PDL-1 and PDL-2. PDL-1 is a B7-related protein that inhibits cell-mediated immune responses by reducing the secretion of IL-2 and IL-10 from memory T cells. This suggests that PDL-1 may be useful in reducing allogenic CD4+ memory T-cell responses to endothelial cells, thereby reducing the likelihood of host immune responses to allografts. At least two isoforms of PDL-1 are known to exist; this antibody is specific to the larger isoform. PDL-1 antibody has no cross-reactivity to PDL-2.
Specifications

Specifications

PD-L1
Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
Unconjugated
Rabbit
Human
Q9NZQ7
29126
Recombit protein representing the C-terminus of PD-L1
Primary
4° C
CD274
BLR020E
Recombinant Monoclonal
Liquid
RUO
BBS with 0.1% BSA and 0.09% sodium azide; pH 8.2
B7-H, B7H1, PD-L1, PDCD1L1, PDCD1LG1, PDL1, B7 homolog 1, CD274 antigen, PDCD1 ligand 1, programmed cell death 1 ligand 1, programmed death ligand 1
CD274
IgG
Purified
Antibody
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