Invitrogen™ PDE10A Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA561465

Catalog No. PIPA561465

Description

Immunogen sequence: TVEKWLKRKN NKSEDESAPK EVSRYQDTNM QGVVYELNSY IEQRLDTGGD NQLLLYELSS IIKIATKADG FALYFLGECN NSLCIFTPPG IKEGKPRLIP AGPITQGTTV SAYVAKSRKT LLVEDILGDE RFPRGTGLES GTRIQSVL Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 94%.

Various cellular responses are regulated by the second messengers cAMP and cGMP. Phosphodiesterases, such as PDE10A, eliminate cAMP- and cGMP-mediated intracellular signaling by hydrolyzing the cyclic nucleotide to the corresponding nucleoside 5-prime monophosphate.

Specifications

• Antigen: PDE10A
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PDE10A
• Gene Alias: ADSD2; cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A; dJ416F21.1 (phosphodiesterase 10A); dual-substrate cAMP and cGMP, cyclic nucleotide phosphodiesterase; FLJ11894; FLJ25677; HSPDE10A; IOLOD; LINC00473; PDE10A; PDE10A19; PDE10A2 brain-specific isoform; Pde10a3; phosphodiesterase 10A; phosphodiesterase 10A1 (PDE10A1); phosphodiesterase 10A7 (PDE10A7); testis-specific phosphodiesterase PDE10A2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10846
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9Y233
• Gene Symbols: PDE10A
• Immunogen: Recombinant protein corresponding to Human PDE10A. Recombinant protein control fragment (Product #RP-90662).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG