Invitrogen™ PDE2A Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA598040

Catalog No. PIPA598040

Description

PDE2A Polyclonal Antibody for Western Blot, ICC/IF, IHC (P), ELISA

PDE2A (phosphodiesterase 2A) is a 100 kD cyclic nucleotide phosphodiesterase (PDE) and three isoforms of PDE2A have been reported (PDE2A1, PDE2A2 and PDE2A3) which arise from a single gene by alternative splicing events. PDE2A can degrade both cAMP and cGMP, but degrades cGMP with greater efficacy. PDE2A is expressed in a variety of tissue types, with greatest expression in the brain, where it is localized in the cerebellum and neocortex. PDE2A has been implicated in penile erectile dysfunction and in the regulation of fluid and inflammatory cell transport across the endothelial cell barrier.

Specifications

• Antigen: PDE2A
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PDE2A
• Gene Alias: c-GMP stimulated phosphodiesterase; cGMP-dependent 3',5'-cyclic phosphodiesterase; cGMP-stimulated cyclic nucleotide phosphodiesterase; cGMP-stimulated phosphodiesterase 1; cGMP-stimulated phosphodiesterase 2; cGMP-stimulated phosphodiesterase 4; cGSPDE; CGS-PDE; cyclic GMP stimulated phosphodiesterase; cyclic GMP-stimulated phosphodiesterase; cyclic nucleotide phosphodiesterase; cyclic nucleotide phosphodiesterase 2a; Pde2; Pde2a; PDE2A1; Pde2a2; PED2A4; phosphodiesterase 2A; phosphodiesterase 2A, cGMP-stimulated
• Host Species: Rabbit
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 5138
• Content And Storage: -20°C or -80°C if preferred
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 3 mg/mL
• Formulation: PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
• Gene Accession No.: O00408
• Gene Symbols: PDE2A
• Immunogen: Recombinant Human cGMP-dependent 3',5'-cyclic phosphodiesterase protein (15-226AA).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG