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Invitrogen™ PDE3B Recombinant Rat Monoclonal Antibody (SMCP3B)

Catalog No. 740069T
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74-006-9T 100 μL
74-006-9TXS 20 μL
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Catalog No. 74-006-9T Supplier Invitrogen™ Supplier No. 740069T
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Rat Recombinant Monoclonal Antibody

Recombinant rat monoclonal antibodies are produced using in vitro expression systems. Recombinant antibodies are produced using specific genes that code for the desired antibodies. These genes are cloned into an expression vector and expressed in vitro. The advantages of recombinant antibodies include better specificity and lot-to-lot consistency. Applications Tested: This SMCP3B antibody has been tested in western blot and immunoprecipitation in 3T3-L1 Adipocyte differentiated cells. It can be used at 1 μg/mL in western blot and 10 μg in immunoprecipitation. This antibody may result in detection of non-specific bands in western blot application along with the band of interest. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.

Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. May play a role in fat metabolism. Regulates cAMP binding of RAPGEF3. Through simultaneous binding to RAPGEF3 and PIK3R6 assembles a signaling complex in which the PI3K gamma complex is activated by RAPGEF3 and which is involved in angiogenesis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PDE3B
Applications Immunoprecipitation, Western Blot
Classification Recombinant Monoclonal
Clone SMCP3B
Concentration 1.0 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene PDE3B
Gene Accession No. Q61409
Gene Alias 9830102A01Rik; AI847709; CGIP1; CGI-PDE B; CGIPDE1; cGMP-inhibited 3',5'-cyclic phosphodiesterase B; cGMP-inhibited 3',5'-cyclic phosphodiesterase B; LOW QUALITY PROTEIN: cGMP-inhibited 3',5'-cyclic phosphodiesterase B; cyclic GMP-inhibited phosphodiesterase B; cyclic nucleotide phosphodiesterase; HcGIP1; LOW QUALITY PROTEIN: cGMP-inhibited 3',5'-cyclic phosphodiesterase B; PDE3B; phosphodiesterase 3B; phosphodiesterase 3B cGMP inhibited; phosphodiesterase 3B, cGMP-inhibited
Gene Symbols PDE3B
Host Species Rat
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18576
Target Species Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG2a κ
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