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PDX1 Rabbit anti-Human, Mouse, Polyclonal, Proteintech
SDP

Catalog No. 501733193 Shop All Proteintech Group Inc Products
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50-173-3193 150 μL
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Catalog No. 50-173-3193 Supplier Proteintech Group Inc Supplier No. 209891AP150UL
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Description

Rabbit Polyclonal Antibody

PDX1 (pancreas duodenum homeobox-1, also known as IPF-1, IDX-1, and STF-1) is a transcription factor that has been shown to activate insulin, glucokinase, IAPP, and somatostatin gene transcription. Significant interest surrounds this proteins glucose-dependent regulation of insulin gene transcription. Additionally, pdx-1 has been studied for its role in pancreatic development which includes maturation and differentiation of pancreatic precursor cells. Mutations in the pdx-1 gene have been shown to cause pancreatic agenesis, maturity-onset diabetes of the young, and type II diabetes.

Specifications

Antigen PDX1
Applications Western Blot
Classification Polyclonal
Concentration 0.27 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene PDX1
Gene Accession No. P52945, P52946
Gene Alias Glucose sensitive factor, GSF, IDX 1, Insulin promoter factor 1, Insulin upstream factor 1, IPF 1, IPF1, Islet/duodenum homeobox 1, IUF 1, IUF1, MODY4, PDX 1, PDX1, STF 1
Gene Symbols PDX1
Host Species Rabbit
Immunogen Peptide
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18609, 3651
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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