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ABclonal Technology PE anti-Human CD170/Siglec-5

Supplier: ABclonal Technology A26119100T

This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes macrophages and neutrophils Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion
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