Cytek Biosciences Inc Antibodies PE Anti-Mouse CD86 (B7-2) (PO3.1) ..... Cat. No. 50-0861-U025 ..... Size 25 µg

Supplier:  Cytek Biosciences Inc 500861U025

Antibodies PE Anti-Mouse CD86 (B7-2) (PO3.1) ..... Cat. No. 50-0861-U025 ..... Size 25 µgThe PO3.1 antibody reacts with mouse CD86, also known as B7-2, an 80 kDa cell surface protein which is a ligand for CD28, a co-stimulatory receptor for the T cell receptor (TCR). CD28 can also bind a second B7 ligand known as CD80 (B7-1). Both CD80 and CD86 are expressed on activated B cells and antigen-presenting cells. These ligands trigger CD28 signaling in concert with TCR activation to drive T cell proliferation, induce high-level expression of IL-2, impart resistance to apoptosis, and enhance T cell cytotoxicity. The interaction / co-stimulatory signaling between the B7 ligands and CD28 provides crucial communication between T cells and B cells or APCs to coordinate the adaptive immune response.The PO3.1 antibody may be used as a marker for CD86 expression on B cells, macrophages, and dendritic cells.

Catalog No. 50-210-3413