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Invitrogen™ Pepsinogen I Recombinant Rabbit Monoclonal Antibody (HL2137)
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Catalog No. FEMA550395
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100 μL
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FEMA550395 100 μL
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Catalog No. FEMA550395 Supplier Invitrogen™ Supplier No. MA550395
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Description

Rabbit Recombinant Monoclonal Antibody

MA5-50395 has sucessfully been used in Indirect ELISA.

PGA5: Pepsinogen 5, group I (pepsinogen A). Pepsinogens are the inactive precursors of pepsin, the major acid protease found in the stomach. Pepsin is one of the main proteolytic enzymes secreted by the gastric mucosa. Pepsin consists of a single polypeptide chain and arises from its precursor, pepsinogen, by removal of a 41 amino acid segment from the N-terminus. Pepsinogen is synthesized in the stomach lining, and hydrochloric acid, also produced by the gastric mucosa, is necessary to convert the inactive enzyme and to maintain the optimum acidity (pH 1-3) for pepsin function. Pepsin is particularly effective in cleaving peptide bonds involving aromatic amino acids. Pepsin shows extremely broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent. PGA5 is a member of the subfamily A1 within the pepsin family and is the predominant endopeptidase in the gastric juice of vertebrates. PGA5 is inhibited by ovUS-1, a uterine serpin.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Pepsinogen I
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone HL2137
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative
Gene Pga5
Gene Accession No. P0DJD9, Q9D106
Gene Alias 1110035E17Rik; Pepf; pepsin A; pepsin A-3; Pepsin A-5; Pepsin F; pepsinogen 3, group I (pepsinogen A); pepsinogen 5, group I; pepsinogen 5, group I (pepsinogen A); pepsinogen A3; pepsinogen A5; pepsinogen F; pepsinogen F protein; pepsinogen-3; Pepsinogen-5; Pg5; PGA3; PGA5
Gene Symbols Pga5
Host Species Rabbit
Immunogen Recombinant fragmemt of human Pepsinogen I.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5222, 58803, 60372
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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