Invitrogen™ Perilipin 1 Monoclonal Antibody (GT2781)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA527861

Catalog No. PIMA527861

Description

Positive Control: mouse adipose Predicted Reactivity: Human (100%), Rat (92%), Pig (92%), Sheep (94%), Bovine (94%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Adipose tissue is an energy reserve in animals and is strictly regulated in nondomestic species. Adipose cells produce and secrete numerous physiologically important proteins, such as lipoprotein lipase (LPL), leptin, adipocyte complement related protein of 30 kDa (Acrp30), resistin, and perilipin. Perilipin is an intracellular neutral lipid droplet protein that is hormonally regulated. This protein is localized exclusively to the surface of lipid droplets. In response to lypotic stimuli, perilipin is phosphorylated by protein kinase A. Once activated, perilipin has inhibitory affects upon hormone-sensitive lipase (HSL), a protein that mediates the hydrolysis of triacylglycerol, the major form of stored energy in the body. Perilipin expression is limited to adipocytes and steroidogenic cells. There are currently two known isoforms, Perilipin A and B. Both of these proteins are encoded by a single-copy gene and are the result of differential splicing events.

Specifications

• Antigen: Perilipin 1
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 20% glycerol and no preservative
• Gene Accession No.: O60240, Q8CGN5
• Gene Symbols: Plin1
• Immunogen: Recombinant protein encompassing a sequence within the center region of human Perilipin 1. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Clone: GT2781
• Conjugate: Unconjugated
• Gene: Plin1
• Gene Alias: 6030432J05Rik; adipocyte lipid droplet binding protein; FPLD4; Lipid droplet-associated protein; PERI; PERIA; perilipin; perilipin 1; perilipin A; perilipin B; perilipin-1; PLIN; PLIN1
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 103968, 5346
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

Safety and Handling

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