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Invitrogen™ Perilipin 1 Polyclonal Antibody, Alexa Fluor™ 488
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Catalog No. PIPA11051A4
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PIPA11051A4 50 μg
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Catalog No. PIPA11051A4 Supplier Invitrogen™ Supplier No. PA11051A488
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Rabbit Polyclonal Antibody

PA1-1051 detects perilipin A from rat and 3T3-L1 cell extract. The PA1-1051 immunogen is a synthetic peptide corresponding to the residues C E(502) P I L G R T Q Y S Q L R K K S(517) of rat Perilipin A. This sequence is 93% conserved in humans. The PA1-1051 immunizing peptide (Cat. # PEP-169) is available for use in neutralization and control experiments.

Adipose tissue is an energy reserve in animals and is strictly regulated in nondomestic species. Adipose cells produce and secrete numerous physiologically important proteins, such as lipoprotein lipase (LPL), leptin, adipocyte complement related protein of 30 kDa (Acrp30), resistin, and perilipin. Perilipin is an intracellular neutral lipid droplet protein that is hormonally regulated. This protein is localized exclusively to the surface of lipid droplets. In response to lypotic stimuli, perilipin is phosphorylated by protein kinase A. Once activated, perilipin has inhibitory affects upon hormone-sensitive lipase (HSL), a protein that mediates the hydrolysis of triacylglycerol, the major form of stored energy in the body. Perilipin expression is limited to adipocytes and steroidogenic cells. There are currently two known isoforms, Perilipin A and B. Both of these proteins are encoded by a single-copy gene and are the result of differential splicing events.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Perilipin 1
Applications Immunocytochemistry
Classification Polyclonal
Concentration 1.0 mg/mL
Conjugate Alexa Fluor 488
Formulation PBS with 1.0mg/mL BSA and 0.05% sodium azide
Gene Plin1
Gene Accession No. P43884, Q8CGN5
Gene Alias 6030432J05Rik; adipocyte lipid droplet binding protein; FPLD4; Lipid droplet-associated protein; PERI; PERIA; perilipin; perilipin 1; perilipin A; perilipin B; perilipin-1; PLIN; PLIN1
Gene Symbols Plin1
Host Species Rabbit
Immunogen Synthetic peptide corresponding to the residues C E(502) P I L G R T Q Y S Q L R K K S(517) of rat Perilipin A.
Purification Method Antigen affinity chromatography
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 103968, 25629
Target Species Mouse, Rat
Content And Storage 4°C, store in dark, DO NOT FREEZE!
Product Type Antibody
Form Liquid
Isotype IgG
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WARNING: Cancer - www.P65Warnings.ca.gov
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