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PERK/EIF2AK3 Rabbit anti-Human, Polyclonal, Proteintech
SDP

Rabbit Polyclonal Antibody

Supplier:  Proteintech Group Inc 243901AP150UL

Encompass_Preferred

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Catalog No. 50-173-4331


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Description

Description

Phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation and thus to a rapid reduction of translational initiation and repression of global protein synthesis. Serves as a critical effector of unfolded protein response (UPR)-induced G1 growth arrest due to the loss of cyclin-D1 (CCND1). Involved in control of mitochondrial morphology and function.
Specifications

Specifications

PERK/EIF2AK3
Polyclonal
Unconjugated
EIF2AK3
EIF2AK3, HRI, HsPEK, Pancreatic eIF2 alpha kinase, PEK, PERK, WRS
Rabbit
Antigen Affinity Chromatography
RUO
9451
-20°C
Liquid
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
0.33 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q9NZJ5
EIF2AK3
PERK/EIF2AK3 Fusion Protein Ag18254
150 μL
Primary
Human
Antibody
IgG
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