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  5. Tocris Bioscience™ PF 04671536 hydrochloride

Tocris Bioscience™ PF 04671536 hydrochloride
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Catalog No. 60245
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60-245 5 mg
60-242-5 25 mg
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Catalog No. 60-245 Supplier Tocris Bioscience™ Supplier No. 6024/5
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Description

Potent and selective PDE8B/8A inhibitor

PF 04671536 hydrochloride is a potent and selective PDE8B/8A inhibitor (IC50 values are 1.3 and 1.9 nM, respectively). Exhibits selectivity for PDE8A/B over other PDEs (IC50 values are >10 μM) and a range of other targets. Increases glucose-dependent insulin secretion from human pacreatic islet cells. Orally bioavailable.

Specifications

Chemical Name or Material 5-Methyl-3-[[(2R)-4-(2-thiazolylmethyl)-2-morpholinyl]methyl]-3H-1,2,3-triazolo[4,5-d]pyrimidin-7-amine hydrochloride
CAS 1305116-67-9
Assay Percent Range >98%
Quantity 5 mg
Molecular Formula C14H18N8OS.HCl
Formula Weight Observed MW: 382.87
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