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AdipoGen PF-2545920 (25 mg)
SDP

Supplier:  AdipoGen AGCR13636M025

Encompass_Preferred

Chemical. CAS: 898562-94-2. Formula: C25H20N4O. MW: 392.5. Potent and selective phosphodiesterase 10A (PDE10A) inhibitor (IC50=1.26nM) in vitro and in vivo. PDE10A is a cGMP and cAMP degrading PDE isozyme with neurological importance and was shown to be implicated in the regulation of energy homeostasis. Inhibition of PDE10A leads to interference of the breakdown of the secondary messenger cAMP and cGMP. Anti-psychotic agent. Useful for the treatment of schizophrenia. Anticancer agent. Inhibits colon tumor cell growth for which high levels of PDE10A have been reported. Antiobesity and antidiabetic agent. Induces browning in white adipose tissue (WAT).

Catalog No. 50-205-4011


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