PGLYRP4 Rabbit anti-Human, Polyclonal, Proteintech

Catalog No.	Quantity
50-173-3274	150 μL

Catalog No. 50-173-3274 Supplier Proteintech Group Inc Supplier No. 211341AP150UL

Description

Rabbit Polyclonal Antibody

The primary immune recognition is based on structures common among invading pathogens. Bacterial surface molecules, such as lipopolysaccharide (LPS) and peptidoglycan (PGN), are known to elicit immune reactions ranging from cytokine release to fever. Recently, a family of proteins called peptidoglycan recognition protein (PGRP) has been identified in mouse and human that binds to peptidoglycans expressed on Gram-positive bacteria. Peptidoglycan (PGN) is an essential cell wall component of virtually all bacteria (1, 2) and, thus, it is an excellent target for recognition by the eukaryotic innate immune system. The PGRPs (PGRP-L, PGRP-S, PGRP-Ia, and PGRP-I beta) define a new family of human pattern recognition molecules (3). PGRP-L is primarily expressed in the liver. Although liver is not considered a primary immune organ, liver participates in host defenses by producing acute phase proteins (by hepatocytes) in response to infections and by clearing microorganisms from blood (4-5).

Specifications

• Antigen: PGLYRP4
• Applications: Immunohistochemistry (Paraffin)
• Classification: Polyclonal
• Concentration: 0.44 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene: PGLYRP4
• Gene Accession No.: Q96LB8
• Gene Alias: PGLYRP4, PGLYRPIbeta, PGRP I beta, PGRP Ibeta, PGRPIB, SBBI67
• Gene Symbols: PGLYRP4
• Host Species: Rabbit
• Immunogen: PGLYRP4 Fusion Protein Ag15539
• Purification Method: Antigen Affinity Chromatography
• Quantity: 150 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 57115
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG