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  6. PGRMC2 Mouse anti-Human, Mouse, Clone: 5F10D7, Proteintech 

PGRMC2 Mouse anti-Human, Mouse, Clone: 5F10D7, Proteintech
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Catalog No. 501736346 Shop All Proteintech Group Inc Products
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50-173-6346 150 μL
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Catalog No. 50-173-6346 Supplier Proteintech Group Inc Supplier No. 602491IG150UL
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Description

Mouse Monoclonal Antibody

PGRMC2 has a calculated molecular weight of 24 kDa. The band of about 28 kDa detected by this monoclonal antibody is unknown but may represent phosphorylated form of PGRMC2.

PGRMC2 (progesterone receptor membrane component 2), also known as DG6 (steroid receptor protein DG6) or PMBP (progesterone membrane-binding protein), is a single pass membrane protein belonging to the cytochrome b5 family (MAPR (membrane associated progesterone receptor) subfamily). Expressed in sperm, PGRMC2 is believed to function as a steroid receptor and may participate in the progesterone-dependent sperm acrosome reaction. PGRMC2 shares approximately 50% overall sequence identity with its close relative PGRMC1. The loss of the gene encoding PGRMC2 is associated with metastasis in uterine endocervical adenocarcinomas, implicating a potential role of PGRMC2 in the suppression of metastasis of endocervical adenocarcinomas.

Specifications

Antigen PGRMC2
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone 5F10D7
Concentration 1.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene PGRMC2
Gene Accession No. O15173, Q80UU9
Gene Alias DG6, PGRMC2, PMBP
Gene Symbols Pgrmc2
Host Species Mouse
Immunogen PGRMC2 Fusion Protein Ag20077
Purification Method Protein A
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10424, 70804
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG2a
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