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Invitrogen™ PGRMC2 Polyclonal Antibody
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Catalog No. PIPA5101661
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100 μL
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PIPA5101661 100 μL
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Catalog No. PIPA5101661 Supplier Invitrogen™ Supplier No. PA5101661
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total PGRMC2.

PGRMC2 (progesterone receptor membrane component 2), also known as DG6 (steroid receptor protein DG6) or PMBP (progesterone membrane-binding protein), is a single pass membrane protein belonging to the cytochrome b5 family (MAPR (membrane associated progesterone receptor) subfamily). Expressed in sperm, PGRMC2 is believed to function as a steroid receptor and may participate in the progesterone-dependent sperm acrosome reaction. PGRMC2 shares approximately 50% overall sequence identity with its close relative PGRMC1. The loss of the gene encoding PGRMC2 is associated with metastasis in uterine endocervical adenocarcinomas, implicating a potential role of PGRMC2 in the suppression of metastasis of endocervical adenocarcinomas.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PGRMC2
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Pgrmc2
Gene Accession No. O15173, Q5XIU9, Q80UU9
Gene Alias 4631434O19Rik; 5730409G06Rik; DG6; Membrane-associated progesterone receptor component 2; Pgrmc2; PMBP; progesterone membrane binding protein; Progesterone membrane-binding protein; progesterone receptor membrane component 2; steroid receptor protein DG6
Gene Symbols Pgrmc2
Host Species Rabbit
Immunogen A synthesized peptide derived from human PGRMC2(Accession O15173), corresponding to amino acid residues F190-D223.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10424, 361940, 70804
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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