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PGRMC2 Polyclonal Antibody, Bethyl Laboratories

Catalog No. 501563899
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50-156-3899 20 μL
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Catalog No. 50-156-3899 Supplier Bethyl Laboratories, Inc Supplier No. A302955AT
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Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt.

PGRMC2 (progesterone receptor membrane component 2), also known as DG6 (steroid receptor protein DG6) or PMBP (progesterone membrane-binding protein), is a single pass membrane protein belonging to the cytochrome b5 family (MAPR (membrane associated progesterone receptor) subfamily). Expressed in sperm, PGRMC2 is believed to function as a steroid receptor and may participate in the progesterone-dependent sperm acrosome reaction. PGRMC2 shares approximately 50% overall sequence identity with its close relative PGRMC1. The loss of the gene encoding PGRMC2 is associated with metastasis in uterine endocervical adenocarcinomas, implicating a potential role of PGRMC2 in the suppression of metastasis of endocervical adenocarcinomas.

Specifications

Antigen PGRMC2
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene PGRMC2
Gene Accession No. O15173
Gene Alias DG6, PMBP
Gene Symbols PGRMC2
Host Species Rabbit
Immunogen Between 173 and 223
Purification Method Antigen affinity chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10424
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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