Phenylacetyl chloride, 98%

Description

CAS: 103-80-0 | C8H7ClO | 154.59 g/mol

Phenylacetyl chloride is used in the preparation of 1,2-diphenyl-ethanone by reaction with iodobenzene using tetrabutylammonium tetrafluoroborate as a phase transfer catalyst. It is widely used in the chemical industry for manufacturing dyes and pharmaceutical products. It plays an important role in the preparation of penicillin. Further, it is used to prepare esters for flavorings.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Phenylacetyl chloride is used in the preparation of 1,2-diphenyl-ethanone by reaction with iodobenzene using tetrabutylammonium tetrafluoroborate as a phase transfer catalyst. It is widely used in the chemical industry for manufacturing dyes and pharmaceutical products. It plays an important role in the preparation of penicillin. Further, it is used to prepare esters for flavorings.

Solubility
Miscible with alcohol and ether.

Notes
Moisture sensitive. Store in a cool place.Incompatible with amines, most common metals, strong bases and strong oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 103-80-0
• Molecular Formula: C8H7ClO
• Molecular Weight (g/mol): 154.59
• MDL Number: MFCD00000729
• InChI Key: VMZCDNSFRSVYKQ-UHFFFAOYSA-N
• Synonym: phenylacetyl chloride, benzeneacetyl chloride, acetyl chloride, phenyl, phenylacetic acid chloride, phenacetyl chloride, phenylacetylchloride, unii-t30899drnd, phenyl acetyl chloride, a-toluoyl chloride, phenylacetyl
• PubChem CID: 7679
• IUPAC Name: 2-phenylacetyl chloride
• SMILES: ClC(=O)CC1=CC=CC=C1

• Density: 1.168
• Boiling Point: 225°C
• Flash Point: 102°C (215°F)
• Refractive Index: 1.5325
• Quantity: 100 g
• UN Number: UN2577
• Beilstein: 742254
• Sensitivity: Moisture sensitive
• Solubility Information: Miscible with alcohol and ether.
• Formula Weight: 154.6
• Percent Purity: 98%
• Chemical Name or Material: Phenylacetyl chloride

Safety and Handling

Hazard Category	H314-H500
Hazard Statement	GHS H Statement H314-H318 Causes severe skin burns and eye damage. Causes serious eye damage.
Precautionary Statement	P260-P264b-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P501c
DOTInformation	Transport Hazard Class: 8; Packing Group: II; Proper Shipping Name: PHENYLACETYL CHLORIDE
EINECSNumber	203-146-5
TSCA	Yes
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only