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  6. Philanthotoxin 74, Tocris Bioscience™

Philanthotoxin 74, Tocris Bioscience™

Catalog No. 27701
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Quantity:
1 mg
10 mg
50 mg
Catalog No. Quantity
27-701 1 mg
27-701-0 10 mg
27-705-0 50 mg
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Catalog No. 27-701

Supplier: R&D Systems 2770/1

This item is not returnable. View return policy

Description

GluA1 and GluA3 selective AMPA antagonist

AMPA receptor antagonist. Non-selective homomeric GluA3 and GluA1 receptor antagonist (IC50 values are 263 and 296 nM respectively). Inhibits homomeric GluA3 and GluA1 with a 100-fold greater potency than heteromeric GluA1/2 and GluA2/3 receptors.

Chemical Identifiers

CAS 1227301-51-0
Molecular Formula C24H44Cl2N4O3
Molecular Weight (g/mol) 507.541
InChI Key HWTJQQMIKVJWLH-IKXQUJFKSA-N
Synonym philanthotoxin 74, philanthotoxin 74 dihydrochloride, phtx-74, philanthotoxin-7,4, phtx-74 dihydrochloride, n-7-4-aminobutyl amino heptyl-nalpha-butanoyl-l-tyrosinamide-hydrogen chloride 1/2, s-n-7-4-aminobutyl amino heptyl-4-hydroxy-?-1-oxobutyl amino benzenepropanamide dihydrochloride, s-n-7-4-aminobutyl amino heptyl-4-hydroxy-alpha-1-oxobutyl amino benzenepropanamide dihydrochloride, n-1s-1-7-4-aminobutyl amino heptyl carbamoyl-2-4-hydroxyphenyl ethyl butanamide dihydrochloride
PubChem CID 46213501
IUPAC Name N-[(2S)-1-[7-(4-aminobutylamino)heptylamino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]butanamide;dihydrochloride
SMILES CCCC(=O)NC(CC1=CC=C(C=C1)O)C(=O)NCCCCCCCNCCCCN.Cl.Cl

Specifications

Quantity 1 mg
Formula Weight 507.54
Percent Purity >98%
Chemical Name or Material Philanthotoxin 74

Safety and Handling

Recommended Storage Desiccate at Room Temperature
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