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  5. MP Biomedicals™ Phorbol-12-myristate-13-acetate, >99%

MP Biomedicals™ Phorbol-12-myristate-13-acetate, >99%

Catalog No. MP215186425 Shop All MP Biomedicals, Inc Products
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MP215186425 25 mg
02-151-86401 1 mg
MP215186410 10 mg
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Description

Phorbol-12-myristate-13-acetate, >99% is a potent tumor promoter and activates protein kinase C in vivo and in vitro.

  • PMA′s effects on PKC are attributed to its similarity to diacylgylerol, a natural activator of PKC.
  • PMA activates Ca2+− ATPase and potentiates forskolin-induced cAMP formation.
  • It has been shown to inhibit apoptosis induced by the Fas antigen, but PMA induces apoptosis in HL-60 promyelocytic leukemia cells.
TRUSTED_SUSTAINABILITY

Specifications

Purity >98% (HPLC)
For Use With (Application) Potent tumor promoter, Activates protein kinase C in vivo and in vitro
Solubility Practically insoluble.
Molecular Formula C36H56O8
CAS 16561-29-8
Content And Storage Store at − 20°C. Protect from light.
Quantity 25 mg
Molecular Weight (g/mol) 616.84 g/mol
Melting Point 162°F
Vapor Pressure 1.8X10-17 mm Hg at 25°C
Form Solid
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use.

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