Learn More
Abcam Phortress, Antitumor Agent, Solid, >98% Purity, 50 mg
Description
- Potency: IC50 values for MCF-7 and MDA468 cells are 40 nM and 158 nM, respectively.
- Activity: Active against breast, ovarian and renal carcinomas; active in vitro and in vivo.
- Mechanism: Taken up into sensitive cells followed by aryl hydrocarbon receptor binding and translocation into the nucleus. Requires metabolic activation by cytochrome P450 to generate cytotoxic species.
- Chemical Properties: Molecular weight 459.4 Da; purity >98%; water soluble.
- Form: Solid.
The product is subject to the following: Abcam Restricted Use Statement
Specifications
Specifications
| Form | Solid |
| Shipping Condition | Ambient |
| Target Molecule | Aryl Hydrocarbon Receptor |
| Content And Storage | Store at -20°C. |
| Formulation | 100% (2S)-2,6-diamino-N-[4-(5-fluoro-1,3-benzothiazol-2-yl)-2-methylphenyl]hexanamide;dihydrochloride |
| Quantity | 50 mg |
| For Use With (Application) | Antitumor research |
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.