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Phospho-53BP1 (Ser25) Rabbit anti-Human, Mouse, Polyclonal, Bethyl Laboratories

Catalog No. 501558133
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50-155-8133 100 μL
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Catalog No. 50-155-8133 Supplier Bethyl Laboratories, Inc Supplier No. A300652A
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

53BP1 (P53-binding protein 1) plays a critical role in tumor suppression and is a putative substrate of ATM kinase. Upon DNA damage, 53BP1 is phosphorylated and localizes to the presumptive sites of damage, specifically, double-strand breaks. 53BP1 may have a role in checkpoint signaling during mitosis, enhances TP53-mediated transcriptional activation, and participates in DNA repair by maintaining genomic stability.

Specifications

Antigen Phospho-53BP1 (Ser25)
Applications Immunohistochemistry, Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.2 mg/ml
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene TP53BP1
Gene Accession No. P70399, Q12888
Gene Alias TP53BP1, p202
Gene Symbols TP53BP1, Trp53bp1
Host Species Rabbit
Immunogen Surrounding serine 25
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 27223, 7158
Target Species Human, Mouse
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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