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Phospho-AKT (Ser473) Mouse anti-Human, Mouse, Clone: 1C10B8, Proteintech
SDP

Mouse Monoclonal Antibody

Supplier:  Proteintech Group Inc 664441IG100UL

Encompass_Preferred

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Catalog No. 50-173-6870


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Description

Description

This antibody detects all the members of AKT with phospho-modification at Ser473.

The Akt family of serine/threonine protein kinases (also called protein kinase B/PKB) plays a key role in insulin signaling, cellular survival, and transformation. Akt1 is activated by phosphorylation on residues threonine 308 and Serine 473. Thr308, in the catalytic domain, is phosphorylated by the protein kinase PDK1, and Ser473, in the COOH-terminal regulatory domain, is phosphorylated by putative serine 473 kinase. To date, a couple of proteins have been shown to physically interact with PKB.
Specifications

Specifications

Phospho-AKT (Ser473)
Monoclonal
1 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P31749, P31750
AKT1
Peptide
100 μL
Primary
Human, Mouse
Antibody
IgG1
Immunohistochemistry (Paraffin), Western Blot
1C10B8
Unconjugated
AKT1
AKT, AKT1, AKT1-phospho-S473, pakt, p-AKT, Phospho akt, PKB, PKB ALPHA, PRKBA, Protein kinase B, Proto oncogene c Akt, RAC, RAC ALPHA, RAC PK alpha
Mouse
Protein G
RUO
11651, 207
-20°C
Liquid
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