Phospho-AKT (Ser473) Mouse anti-Human, Mouse, Clone: 1C10B8, Proteintech

Catalog No.	Quantity
50-173-6870	100 μL

Catalog No. 50-173-6870 Supplier Proteintech Group Inc Supplier No. 664441IG100UL

Description

Mouse Monoclonal Antibody

This antibody detects all the members of AKT with phospho-modification at Ser473.

The Akt family of serine/threonine protein kinases (also called protein kinase B/PKB) plays a key role in insulin signaling, cellular survival, and transformation. Akt1 is activated by phosphorylation on residues threonine 308 and Serine 473. Thr308, in the catalytic domain, is phosphorylated by the protein kinase PDK1, and Ser473, in the COOH-terminal regulatory domain, is phosphorylated by putative serine 473 kinase. To date, a couple of proteins have been shown to physically interact with PKB.

Specifications

• Antigen: Phospho-AKT (Ser473)
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Classification: Monoclonal
• Clone: 1C10B8
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene: AKT1
• Gene Accession No.: P31749, P31750
• Gene Alias: AKT, AKT1, AKT1-phospho-S473, pakt, p-AKT, Phospho akt, PKB, PKB ALPHA, PRKBA, Protein kinase B, Proto oncogene c Akt, RAC, RAC ALPHA, RAC PK alpha
• Gene Symbols: AKT1
• Host Species: Mouse
• Immunogen: Peptide
• Purification Method: Protein G
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 11651, 207
• Target Species: Human, Mouse
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1