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Invitrogen™ Phospho-ATR (Ser428) Recombinant Rabbit Monoclonal Antibody (7F9W10)
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Catalog No. FEMA551545
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FEMA551545 100 μL
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Catalog No. FEMA551545 Supplier Invitrogen™ Supplier No. MA551545
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Description

Rabbit Recombinant Monoclonal Antibody

Immunogen sequence: GISPK.

The protein encoded by this gene is a serine/threonine kinase and DNA damage sensor, activating cell cycle checkpoint signaling upon DNA stress. The encoded protein can phosphorylate and activate several proteins involved in the inhibition of DNA replication and mitosis, and can promote DNA repair, recombination, and apoptosis. This protein is also important for fragile site stability and centrosome duplication. Defects in this gene are a cause of Seckel syndrome 1.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-ATR (Ser428)
Applications ELISA, Western Blot
Classification Recombinant Monoclonal
Clone 7F9W10
Concentration 0.215 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA, 50% glycerol and 0.05% ProClin 300; pH 7.3
Gene ATR
Gene Accession No. Q13535
Gene Alias 2310008J16Rik; 2810405N18Rik; ataxia telangiectasia and Rad3 related; ataxia telangiectasia and Rad3-related protein; ATR; ATR serine/threonine kinase; EC 2.7.11.1; FCTCS; FRAP-related protein 1; FRAP-related protein-1; FRP1; I79_000761; kinase ATR; MEC1; MEC1, mitosis entry checkpoint 1, homolog; protein kinase ATR; SCKL; SCKL1; Serine/threonine-protein kinase ATR; TEM8
Gene Symbols ATR
Host Species Rabbit
Immunogen A synthetic phosphorylated peptide around S428 of human ATR (NP_001175.2).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 545
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Format Liquid
Isotype IgG
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