Invitrogen™ Phospho-ATR (Thr1989) Recombinant Rabbit Monoclonal Antibody (HL132)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA536263

Catalog No. PIMA536263

Description

Phospho-ATR (Thr1989) Recombinant Monoclonal Antibody for Western Blot, ICC/IF, IHC (P)

The protein encoded by this gene is a serine/threonine kinase and DNA damage sensor, activating cell cycle checkpoint signaling upon DNA stress. The encoded protein can phosphorylate and activate several proteins involved in the inhibition of DNA replication and mitosis, and can promote DNA repair, recombination, and apoptosis. This protein is also important for fragile site stability and centrosome duplication. Defects in this gene are a cause of Seckel syndrome 1.

Specifications

• Antigen: Phospho-ATR (Thr1989)
• Classification: Recombinant Monoclonal
• Concentration: 2 mg/mL
• Formulation: PBS with no preservative
• Gene Accession No.: Q13535, Q9JKK8
• Gene Symbols: ATR
• Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human ATR (phospho Thr1989). The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Clone: HL132
• Conjugate: Unconjugated
• Gene: ATR
• Gene Alias: 2310008J16Rik; 2810405N18Rik; ataxia telangiectasia and Rad3 related; ataxia telangiectasia and Rad3-related protein; ATR; ATR serine/threonine kinase; EC 2.7.11.1; FCTCS; FRAP-related protein 1; FRAP-related protein-1; FRP1; I79_000761; kinase ATR; MEC1; MEC1, mitosis entry checkpoint 1, homolog; protein kinase ATR; SCKL; SCKL1; Serine/threonine-protein kinase ATR; TEM8
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 245000, 545
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid