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Invitrogen™ Phospho-Aurora B/C (Thr236, Thr202) Polyclonal Antibody
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Catalog No. PIPA536030
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PIPA536030 100 μL
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Catalog No. PIPA536030 Supplier Invitrogen™ Supplier No. PA536030
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Description

Rabbit Polyclonal Antibody

This antibody detects endogenous protein at a molecular weight of 35 and 39 kDa. Purity is >95% by SDS-PAGE.

Aurora kinases belong to a highly conserved family of mitotic serine/threonine kinases with three members identified among mammals: Aurora A, B, and C. Studies on the temporal expression pattern and subcellular localization of Aurora kinases in mitotic cells suggest an association with mitotic structure. Aurora kinase functional influences span from G2 phase to cytokinesis and may be involved in key cell cycle events such as centrosome duplication, chromosome bi-orientation and segregation, cleavage furrow positioning, and ingression.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-Aurora B/C (Thr236, Thr202)
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 15mM sodium azide; pH 7.2
Gene AURKC
Gene Accession No. O55099, O70126, O88445, Q96GD4, Q9UQB9
Gene Alias AIE1; AIE2; Aik2; AIK3; Aim1; AIM-1; AIRK2; AIRK3; AL022959; ARK2; ARK-2; ARK3; ARK-3; AurB; AurC; Aurkb; aurkb-sv1; aurkb-sv2; Aurkc; Aurora 1; aurora 3; Aurora- and IPL1-like midbody-associated protein 1; aurora B; aurora kinase B; aurora kinase B-Sv1; aurora kinase B-Sv2; aurora kinase C; aurora/Ipl1/Eg2 protein 1; aurora/IPL1/EG2 protein 2; aurora/IPL1-related kinase 2; Aurora/IPL1-related kinase 3; aurora-1; aurora-B; aurora-C; aurora-related kinase 2; aurora-related kinase 3; epididymis secretory protein Li 90; HEL-S-90; IAK3; IPL1; PPP1R48; protein phosphatase 1, regulatory subunit 48; serine/threonine kinase 12; serine/threonine kinase 13 (aurora/IPL1-like); serine/threonine kinase 13 (aurora/IPL-like); serine/threonine kinase 5; serine/threonine-protein kinase 12; Serine/threonine-protein kinase 13; serine/threonine-protein kinase 5; Serine/threonine-protein kinase aurora-B; serine/threonine-protein kinase aurora-C; SPGF5; Stk1; STK-1; STK12; Stk13; Stk5
Gene Symbols AURKB, AURKC
Host Species Rabbit
Immunogen Synthetic phosphopeptide derived from human AURKB/C around the phosphorylation site of Threonine 236/202.
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 114592, 20871, 20877, 292554, 6795, 9212
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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