Invitrogen™ Phospho-BIK (Thr33) Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA536706

Catalog No. PIPA536706

Description

This antibody detects endogenous protein at a molecular weight of 23 kDa. Purity is >95% by SDS-PAGE.

The Bik protein is known to interact with cellular and viral survival-promoting proteins, such as BCL2 and the Epstein-Barr virus in order to enhance programmed cell death. Because its activity is suppressed in the presence of survival-promoting proteins, this protein is suggested as a likely target for antiapoptotic proteins. This protein shares a critical BH3 domain with other death-promoting proteins, BAX and BAK.

Specifications

• Antigen: Phospho-BIK (Thr33)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: BIK
• Gene Alias: apoptosis inducer NBK; apoptosis-inducing NBK; BBC1; BCL2 interacting killer; bcl-2-interacting killer; BCL2-interacting killer; BCL2-interacting killer (apoptosis-inducing); bhikhari; BIK; Bik-like killer protein; Biklk; BIP 1; BIP1; Blk; BP 4; BP4; cb 60; natural born killer; NBK
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 638
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.05% sodium azide; pH 7.2
• Gene Accession No.: Q13323
• Gene Symbols: BIK
• Immunogen: Synthetic phosphopeptide derived from human BIK/ NBK around the phosphorylation site of Threonine 33.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG