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Invitrogen™ Phospho-BRG1 (Ser610) Polyclonal Antibody
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Catalog No. PIPA5105089
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PIPA5105089 100 μL
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Catalog No. PIPA5105089 Supplier Invitrogen™ Supplier No. PA5105089
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of BRG1 only when phosphorylated at Ser610.

Brg1 (Brahma-related gene 1) is an ATPase subunit of SWI2/SNF2-like chromatin-remodeling complexes that enable access of regulatory and effector proteins in transcription, DNA repair and DNA replication. Although Brg1-containing complexes are not essential for general cell survival, they participate in transcriptional regulation of several hundred genes including those involved in interferon and stress response, immune cells differentiation, neurogenesis, cell cycle etc. and is absolutely necessary for mouse embryogenesis. Brg1 is also involved in cell growth arrest, senescence and tumour supression.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-BRG1 (Ser610)
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Smarca4
Gene Accession No. P51532, Q3TKT4, Q8K1P7
Gene Alias ATP-dependent helicase SMARCA4; b2b508.1Clo; b2b692Clo; BAF190; BAF190A; brahma protein-like 1; BRG1; brg-1; BRG1-associated factor 190A; BRM/SWI2-related gene 1; CSS4; FLJ39786; global transcription activator homologous sequence; homeotic gene regulator; HP1-BP72; hSNF2b; mitotic growth and transcription activator; MRD16; nuclear protein GRB1; protein brahma homolog 1; Protein BRG-1; RTPS2; SMARCA4; SNF2; Snf2b; SNF2beta; SNF2-beta; SNF2L4; SNF2LB; SNF2-like 4; sucrose nonfermenting-like 4; SW1/SNF; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4; SWI2; transcription activator BRG1
Gene Symbols Smarca4
Host Species Rabbit
Immunogen A synthesized peptide derived from human SMARCA4(Accession P51532), corresponding to amino acid residues around phosphorylated Ser610.
Purification Method Sequential Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 171379, 20586, 6597
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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