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Invitrogen™ Phospho-C/EBP alpha (Thr226) Polyclonal Antibody
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Catalog No. PIPA536789
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PIPA536789 100 μL
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Catalog No. PIPA536789 Supplier Invitrogen™ Supplier No. PA536789
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Description

Rabbit Polyclonal Antibody

This antibody detects endogenous protein at a molecular weight of 30 and 45 kDa. Purity is >95% by SDS-PAGE.

The C/EBP (CCAAT/enhancer binding protein) family of transcription factors--alpha, beta, delta, and epsilon)--are widely expressed proteins found in a variety of tissues. These domains contain an evolutionarily conserved five-amino acid motif (the regulatory domain motif RDM) that conforms to the consensus sequence (I/V/L) KXEP. One of the major roles of these transcription factors is that of metabolic regulation in liver and fat cells. Studies suggest that these transcription factors act in a cascade aiding in the development of the adipose cell. Three C/EBP beta isoforms (LAP*, LAP, and LIP) arise from different translation initiation and display different function in gene regulation. From a neurological standpoint, C/EBPs have been implicated in the mediation of nerve growth factor, altering synaptic plasticity, and mediation of inflammatory response in AD patients.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-C/EBP alpha (Thr226)
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% sodium azide; pH 7.2
Gene CEBPA
Gene Accession No. P05554, P49715, P53566
Gene Alias C EBP; C/EBP; c/EBP alpha; C/EBPa; C/ebpalpha; C/EBP-alpha; CAAT/enhancer-binding protein DNA-binding protein; CAAT/enhancer-binding protein, DNA-binding protein; CBF-A; CCAAT enhancer binding protein alpha; CCAAT/enhancer binding protein (C/EBP), alpha; CCAAT/enhancer binding protein alpha; CCAAT/enhancer binding protein, alpha; CCAAT/enhancer-binding protein alpha; Cebp; Cebpa; DBPCEP; OTTHUMP00000220269
Gene Symbols CEBPA
Host Species Rabbit
Immunogen Synthetic phosphopeptide derived from human C/EBP alpha around the phosphorylation site of Threonine 226.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1050, 12606, 24252
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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