Invitrogen™ Phospho-c-Fos (Thr232) Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ 44280G

Catalog No. 44-280-G

Description

Phospho-c-Fos (Thr232) Polyclonal Antibody for Western Blot, ICC/IF, IHC (P), ChIP

FBJ murine osteosarcoma viral oncogene homolog is commonly known as Cellular protooncogene Fos (c-Fos). It belongs to the fos transcription factor family and is encoded by the C-FOS gene located on chromosome 14. c-Fos heterodimerizes with c-Jun to form the Activator Protein -1 (AP-1) transcription factor which regulates transcription of several genes that play an important role in cellular signal transduction, cell proliferation and differentiation. c-Fos has been shown to be phosphorylated by various stimuli including growth factors and insulin at atleast seven different sites. The best known upstream kinase for phosphorylation at Threonine 232 is ERK MAPK which regulates localization of c-Fos to the nucleus and is thus important for c-Fos induced transcriptional activity.

Specifications

• Antigen: Phospho-c-Fos (Thr232)
• Classification: Polyclonal
• Formulation: Dulbecco's PBS with 1mg/mL BSA and 0.05% sodium azide; pH 7.3
• Gene Accession No.: P01100
• Gene Symbols: FOS
• Immunogen: The antiserum was produced against a chemically synthesized phosphopeptide derived from the region of human c-Fos that contains threonine 232. The sequence is conserved in mouse and rat.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: ChIP Assay, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Conjugate: Unconjugated
• Gene: FOS
• Gene Alias: activator protein 1; AP-1; cellular oncogene c-fos; cellular oncogene fos; cFos; C-FOS; c-fos oncogene; c-fos protooncogene protein; D12Rfj1; FBJ murine osteosarcoma viral (v-fos) oncogene homolog (oncogene FOS); FBJ murine osteosarcoma viral oncogene homolog; FBJ murine osteosarcoma viral oncogene homolog B; FBJ osteosarcoma oncogene; FBJ osteosarcoma oncogene B; FBJ osteosarcoma viral oncogene isoform deltaFosb-2; FOS; Fos proto-oncogene, AP-1 trancription factor subunit; Fos proto-oncogene, AP-1 transcription factor subunit; Fosb; FosB proto-oncogene, AP-1 transcription factor subunit; fra-2; G0/G1 switch regulatory protein 7; G0S7; I79_009428; p55; protein fosB; proto-oncogene cFOS; proto-oncogene c-Fos; proto-oncogene protein c-fos; v-fos FBJ murine osteosarcoma viral oncogene homolog
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 2353
• Content And Storage: -20°C
• Form: Liquid