Invitrogen™ Phospho-c-Jun (Ser63) Monoclonal Antibody (GT653)

Catalog No.	Quantity
PIMA527760	100 μL

Catalog No. PIMA527760

Supplier: Invitrogen™ MA527760

Description

Mouse Monoclonal Antibody

Positive Control: 293T (25 μg/mL Anisomycin treatment for 30 min) Predicted Reactivity: Mouse (100%), Rabbit (100%), Rhesus Monkey (100%), Bovine (100%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

c-Jun is a transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. It promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. Involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer (CRC) cells.

Specifications

• Antigen: Phospho-c-Jun (Ser63)
• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Classification: Monoclonal
• Clone: GT653
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with no preservative
• Gene: JUN
• Gene Accession No.: P05412, P17325
• Gene Alias: Activator protein 1; AH119; AP1; AP-1; Avian sarcoma virus 17 (v-jun) oncogene homolog; cjun; c-Jun; c-jun transcription factor; enhancer-binding protein AP1; I79_009953; immediate early; JUN; Jun A; Jun activation domain binding protein; Jun oncogene; jun proto-oncogene; Jun proto-oncogene, AP-1 transcription factor subunit; Junc; JUND; p39; proto-oncogene c-Jun; Rjg-9; transcription factor; transcription factor AP-1; V-jun avian sarcoma virus 17 oncogene homolog; v-jun sarcoma virus 17 oncogene homolog
• Gene Symbols: JUN
• Host Species: Mouse
• Immunogen: Carrier-protein conjugated synthetic peptide surrounding phospho Ser63 of human c-Jun. The exact sequence is proprietary.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 24516, 3725
• Target Species: Human, Rat
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG2a