Invitrogen™ Phospho-c-Jun (Ser73) Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ 44292G

Catalog No. 44-292-G

Description

Phospho-c-Jun (Ser73) Polyclonal Antibody for Western Blot, ICC/IF

c-Jun is a transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. It promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. Involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer (CRC) cells.

Specifications

• Antigen: Phospho-c-Jun (Ser73)
• Classification: Polyclonal
• Formulation: Dulbecco's PBS with 1mg/mL BSA and 0.05% sodium azide; pH 7.3
• Gene Accession No.: P05412, P05627
• Gene Symbols: JUN
• Immunogen: The antiserum was produced against a chemically synthesized phosphopeptide derived from the region of human c-Jun that contains serine 73. The sequence is conserved among many species including mouse, rat and chicken.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

• Applications: Western Blot, Immunocytochemistry
• Conjugate: Unconjugated
• Gene: JUN
• Gene Alias: Activator protein 1; AH119; AP1; AP-1; Avian sarcoma virus 17 (v-jun) oncogene homolog; cjun; c-Jun; c-jun transcription factor; enhancer-binding protein AP1; I79_009953; immediate early; JUN; Jun A; Jun activation domain binding protein; Jun oncogene; jun proto-oncogene; Jun proto-oncogene, AP-1 transcription factor subunit; Junc; JUND; p39; proto-oncogene c-Jun; Rjg-9; transcription factor; transcription factor AP-1; V-jun avian sarcoma virus 17 oncogene homolog; v-jun sarcoma virus 17 oncogene homolog
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 16476, 3725
• Content And Storage: -20°C
• Form: Liquid