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Invitrogen™ Phospho-Calmodulin 1/2/3 (Thr80, Ser82) Polyclonal Antibody
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Catalog No. PIPA5104932
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PIPA5104932 100 μL
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Catalog No. PIPA5104932 Supplier Invitrogen™ Supplier No. PA5104932
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of Calmodulin1/2/3 only when phosphorylated at Thr80 + Ser82, which site historically referenced as Thr79+Ser81.

Calmodulin is a small, highly conserved calcium binding protein found in all eukaryotic cells. With the capacity to bind up to four calcium ions, this 17 kDa protein acts as an important intracellular receptor for regulatory calcium signals. As it binds calcium, calmodulin undergoes conformational changes which can increase its affinity for target proteins. It acts both directly, through interaction with key target enzymes, and indirectly, via specific kinases. Studies have found that calmodulin participates in the regulation of several biological processes including energy and biosynthetic metabolism, cell motility, exocytosis, cytoskeletal assembly, and intracellular modulation of both cAMP and calcium concentrations.
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Specifications

Antigen Phospho-Calmodulin 1/2/3 (Thr80, Ser82)
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene CALM1
Gene Accession No. P0DP23, P0DP24, P0DP25, P0DP26, P0DP27, P0DP28, P0DP29, P0DP30, P0DP31
Gene Alias 1500001E21Rik; AI256814; AI327027; AI461935; AL024000; AL024017; Calm; CALM1; Calm2; CALM3; CALML2; calmodulin; calmodulin 1; Calmodulin 1 (phosphorylase kinase, delta); calmodulin 2; calmodulin 2 (phosphorylase kinase, delta); calmodulin 3; calmodulin 3 (phosphorylase kinase, delta); Calmodulin III; Calmodulin-1; Calmodulin-2; Calmodulin-3; Cam; CAM1; Cam2; CAM3; CaMA; CAMB; CAMC; CAMI; CAMII; CAMIII; CPVT4; DD132; epididymis secretory protein Li 72; HEL-S-72; LP7057 protein; LQT14; LQT15; PHKD; PHKD2; PHKD3; phosphorylase kinase delta; phosphorylase kinase subunit delta; phosphorylase kinase, delta subunit; prepro-calmodulin 1; prepro-calmodulin 2; prepro-calmodulin 3; R75142; RNCAMIII
Gene Symbols CALM1, CALM2, CALM3
Host Species Rabbit
Immunogen A synthesized peptide derived from human CALM1(Accession P0DP23), corresponding to amino acid residues around phosphorylated Ser82.
Purification Method sequential chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12313, 12314, 12315, 24242, 24244, 50663, 801, 805, 808
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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