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Invitrogen™ Phospho-CDC25C (Ser216) Polyclonal Antibody
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Catalog No. PIPA5104244
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PIPA5104244 100 μL
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Catalog No. PIPA5104244 Supplier Invitrogen™ Supplier No. PA5104244
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of CDC25C only when phosphorylated at Serine 216.

M-phase inducer phosphatase 3is an enzyme that in humans is encoded by theCDC25Cgene. This gene is highly conserved during evolution and it plays a key role in the regulation of cell division. The encoded protein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 (CDK1) and triggers entry into mitosis. Also, it is thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-CDC25C (Ser216)
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Cdc25c
Gene Accession No. P30307, P48967
Gene Alias CDC25; CDC25C; Cdc25m1; cell division cycle 25C; dual specificity phosphatase CDC25C; EC 3.1.3.48; mitosis inducer CDC25; M-phase inducer phosphatase 3; MPIP3; OTTHUMP00000159490; OTTHUMP00000224012; OTTHUMP00000224013; OTTHUMP00000224016; phosphotyrosine phosphatase; PPP1R60; protein phosphatase 1, regulatory subunit 60
Gene Symbols Cdc25c
Host Species Rabbit
Immunogen A synthesized peptide derived from human CDC25C(Accession P30307), corresponding to amino acid residues around phosphorylated Ser216.
Purification Method Sequential Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12532, 995
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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