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Phospho-Cdc6 (Ser54) Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501986436
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50-198-6436 100 μL
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Catalog No. 50-198-6436 Supplier Bioss Supplier No. BS5246R
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Description

Rabbit Polyclonal Antibody

The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins.

Specifications

Antigen Phospho-Cdc6 (Ser54)
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene CDC6
Gene Accession No. Q99741
Gene Alias CDC18(S.pombe); CDC18L; Cdc18-related protein; CDC6; CDC6 cell division cycle 6 homolog; CDC6-related protein; Cell division control protein 6 homolog; cell division cycle 6; cell division cycle 6 homolog; HsCdc18; HsCDC6; p62(cdc6)
Gene Symbols CDC6
Host Species Rabbit
Immunogen KLH conjugated synthetic phosphopeptide derived from human Cdc6 around the phosphorylation site of Ser54 [PL (p-S)PR].
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 990
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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