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Invitrogen™ Phospho-CDK5 (Tyr15) Polyclonal Antibody

Catalog No. PIPA577909
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PIPA577909 100 μL
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Catalog No. PIPA577909 Supplier Invitrogen™ Supplier No. PA577909

Rabbit Polyclonal Antibody

Positive Control: HeLa Predicted Reactivity: Mouse (100%), Rat (100%), Zebrafish (100%), Xenopus laevis (100%), Pig (100%), Chicken (100%), Sheep (100%), Rhesus Monkey (100%), Bovine (100%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

CDK5 is a member of the Cyclin-Dependent Kinase family that is most abundant in the mammalian brain. Active form of CDK5, which has also been called neuronal cdc2-like kinase, is a heterodimer of CDK5 and a 25 kDa protein which is derived proteolytically from a 35 kDa brain and neuron-specific protein and is essential for the kinase activity of CDK5. CDK5 has emerged as a crucial regulator of neuronal migration in the developing central nervous system. CDK5 phosphorylates a diverse list of substrates, implicating it in the regulation of a range of cellular processes - from adhesion and motility, to synaptic plasticity and drug addiction.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-CDK5 (Tyr15)
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7
Gene CDK5
Gene Accession No. P49615, Q00535, Q03114
Gene Alias AW048668; Cdk5; CDK5 activator 1; CDK5-SV; CDKN5; Cell division protein kinase 5; CR6 protein kinase; Crk6; cyclin dependent kinase 5; cyclin-dependent kinase 5; cyclin-dependent-like kinase 5; LIS7; protein kinase CDK5 splicing; PSSALRE; Serine/threonine-protein kinase PSSALRE; tau protein kinase II catalytic subunit; TPKII catalytic subunit
Gene Symbols CDK5
Host Species Rabbit
Immunogen Carrier-protein conjugated synthetic peptide surrounding phospho Tyr15 of human CDK5. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1020, 12568, 140908
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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WARNING: Cancer - www.P65Warnings.ca.gov
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