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Invitrogen™ Phospho-CNOT2 (Ser101) Polyclonal Antibody
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Catalog No. PIPA537668
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100 μL
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PIPA537668 100 μL
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Catalog No. PIPA537668 Supplier Invitrogen™ Supplier No. PA537668
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Description

Rabbit Polyclonal Antibody

A suggested positive control for IHC is human brain tissue.

CCR4-NOT Transcription Complex 2 (CNOT2) is a component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. CNOT2 is required for the CCR4-NOT complex structural integrity. It can repress transcription and may link the CCR4-NOT complex to transcriptional regulation; the repressive function may specifically involve the N-Cor repressor complex containing HDAC3, NCOR1 and NCOR2. CNOT2 is involved in the maintenance of embryonic stem (ES) cell identity. (UniProt).
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-CNOT2 (Ser101)
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Cnot2
Gene Accession No. Q8C5L3, Q9NZN8
Gene Alias 2600016M12Rik; 2810470K03Rik; AA537049; AA959607; AW557563; C79650; CCR4-associated factor 2; CCR4-NOT transcription complex subunit 2; CCR4-NOT transcription complex, subunit 2; CDC36; CNOT2; HSPC131; MSTP046; negative regulator of transcription 2; NOT2; NOT2H
Gene Symbols Cnot2
Host Species Rabbit
Immunogen Peptide sequence around phosphorylation site of Serine101(S-L-S(p)-Q-G) derived from Human CNOT2.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 299805, 4848, 72068
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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