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Invitrogen™ Phospho-Cofilin (Ser3) Polyclonal Antibody
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Catalog No. 441072G
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44-107-2G 100 μL
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Catalog No. 44-107-2G Supplier Invitrogen™ Supplier No. 441072G
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Description

Rabbit Polyclonal Antibody

Phospho-Cofilin (Ser3) Polyclonal Antibody for ICC/IF, Western Blot

Cofilin binds to F-actin and exhibits pH-sensitive F-actin depolymerizing activity. Regulates actin cytoskeleton dynamics. Important for normal progress through mitosis and normal cytokinesis. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required for the up-regulation of atypical chemokine receptor ACKR2 from endosomal compartment to cell membrane, increasing its efficiency in chemokine uptake and degradation. Required for neural tube morphogenesis and neural crest cell migration.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-Cofilin (Ser3)
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Conjugate Unconjugated
Formulation Dulbecco's PBS with 1mg/mL BSA and 0.05% sodium azide; pH 7.3
Gene CFL1
Gene Accession No. P18760, P23528, P45592
Gene Alias 18 kDa phosphoprotein; AA959946; CFL; Cfl1; CFL-1; Cof; COF1; cofilin; cofilin 1; cofilin 1 (non-muscle); cofilin 1, non-muscle; cofilin, non-muscle isoform; Cofilin1; Cofilin-1; cofilin-1-like protein; epididymis secretory protein Li 15; HEL-S-15; n-cofilin; p18
Gene Symbols CFL1
Host Species Rabbit
Immunogen The antiserum was produced against a chemically synthesized phosphopeptide derived from a region of human cofilin that contains serine 3. The sequence is conserved in mouse and rat.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1072, 12631, 29271, 476022
Target Species Human, Mouse, Rat, Canine
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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