Invitrogen™ Phospho-DNM1L (Ser616) Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5101030

Catalog No. PIPA5101030

Description

Antibody detects endogenous levels of DRP1 only when phosphorylated at Ser616.

A human dynamin-related protein, DRP1 contributes to mitochondrial division in mammalian cells. It plays this important role in mitochondrial fission at steady state and during apoptosis. DRP1 is required for proper cellular distribution of mitochondria, and in mutant neurons, mitochondria are largely absent from synapses, thus providing a genetic tool to assess the role of mitochondria at synapses.

Specifications

• Antigen: Phospho-DNM1L (Ser616)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DNM1L
• Gene Alias: 6330417M19Rik; AI450666; C-terminal region; Dlp1; dnm1l; Dnm1p/Vps1p-like protein; Dnml1; Dnmlp1; Drp1; DVLP; DYMPLE; dynamin 1 like; dynamin 1-like; dynamin family member proline-rich carboxyl-terminal domain less; Dynamin-1-like protein; Dynamin-1-like protein-like protein; Dynamin-like protein; dynamin-like protein 1; dynamin-like protein 4; Dynamin-like protein IV; dynamin-related protein 1; DYNIV 11; DYNIV-11; EC 3.6.5.5; EGK_03514; EMPF; FLJ41912; HDYNIV; N-terminal region; python; similar to dynamin 1-like; VPS1; zgc:66163
• Host Species: Rabbit
• Purification Method: Sequential Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10059, 74006
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: O00429, Q8K1M6
• Gene Symbols: DNM1L
• Immunogen: A synthesized peptide derived from human DNM1L(Accession O00429), corresponding to amino acid residues around phosphorylated Ser616.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov